What does diffuse liver disease mean?

What does diffuse liver disease mean?

Diffuse liver disease generally refers to acute liver disease, fatty liver, chronic liver disease and cirrhosis. Ultrasound is a useful tool in evaluating diffuse liver disease. The ultrasound findings of diffuse liver dis- ease are as follows. Ultrasound findings of acute hepatitis.

What causes diffuse liver?

Diffuse disease occurs as the hepatocytes are damaged and liver function decreases. Disease processes that affect the liver diffusely include infections, fatty infiltration, and liver fibrosis.

Does liver disease show up on an MRI?

MRI, or magnetic resonance imaging, can help detect certain liver disorders that affect this organ. These include hepatitis, hemochromatosis, and fatty liver disease. MRI scans also show blood flow, providing valuable information about any possible disorders of the vascular system associated with the liver.

How is diffuse liver disease treated?

Prednisone and prednisolone, which cause less sodium retention, may prove to be the best drugs to use. Difficulty often arises in distinguishing subacute hepatitis from extra-hepatic biliary obstruction. While the various liver function tests often resolve this problem, they are on occasion unhelpful.

What is the meaning of diffuse fatty liver?

Fatty liver disease means you have extra fat in your liver. You might hear your doctor call it hepatic steatosis. Heavy drinking makes you more likely to get it. Over time, too much alcohol leads to a buildup of fat inside your liver cells. This makes it harder for your liver to work.

Can MRI diagnose cirrhosis?

Cirrhosis can be diagnosed by radiology testing such as computed tomography (CT), ultrasound or magnetic resonance imaging (MRI) or via a needle biopsy of the liver. A new imaging technique called elastography, which can be performed with ultrasound or MRI, can also diagnosis cirrhosis.

Can you get rid of non alcoholic fatty liver disease?

If you have NASH, no medication is available to reverse the fat buildup in your liver. In some cases, the liver damage stops or even reverses itself. But in others, the disease continues to progress. If you have NASH, it’s important to control any conditions that may contribute to fatty liver disease.

How long does it take for a fatty liver to turn into cirrhosis?

It used to be thought that progression from early stage NAFLD to cirrhosis took decades, but recent studies have shown that some people progress rapidly within 2 years.

What does cirrhosis look like on an MRI?

At MR imaging, cirrhotic livers show changed morphologic features, which may include irregular contours, atrophy of certain segments (usually segment IV), peripheral atrophy, and hypertrophy of some segments such as the caudate lobe and the adjacent portion of the right lobe (Fig 4).

What can mimic cirrhosis of the liver?

Conditions that can mimic cirrhosis on imaging include pseudocirrho- sis of treated breast cancer metastases to the liver, fulminant hepatic failure, miliary metasta- ses, sarcoidosis, schistosomiasis, congenital hepatic fibrosis, idiopathic portal hypertension, early primary biliary cirrhosis, chronic Budd-Chiari …

Can MRI diagnose and quantify diffuse liver disease?

Current and developing MRI techniques for detecting and quantifying biomarkers of diffuse liver disease are poised to provide game changing technology for diagnosis, monitoring of disease, and for therapy development. Footnotes Conflict of interest disclosure The authors declared no conflicts of interest.

When is MRI indicated in the workup of fatty liver disease?

Active inflammation. MRI may be used as a diagnostic aid in patients who have equivocal elevation of liver enzyme levels and nonspecific symptoms and in patients who are suspected of having fatty liver disease. Nonalcoholic fatty liver disease is a disorder of abnormal lipid accumulation within the hepatocytes.

What is the role of imaging in the workup of liver disease?

Imaging plays a critical role in the diagnosis and treatment of diffuse liver disease by detecting its presence, determining its distribution and severity, and identifying associated complications, such as cirrhosis, portal hypertension, and malignant disease.

Which radiologic findings are characteristic of amyloidosis of the liver?

Radiologic findings of amyloidosis are mostly nonspecific. On sonographic evaluation, the liver is enlarged and inhomogeneous in echotexture. On CT, findings also include hepatomegaly, and areas of low attenuation can occasionally be seen in focal areas of amyloid deposition.