What is a H1299 cell line?
H1299, also known as NCI-H1299 or CRL-5803, is a human non-small cell lung carcinoma cell line derived from the lymph node, which is widely used in research. As with other immortalized cell lines, H1299 cells can divide indefinitely.
What is H1975 cell line?
NCI-H1975 [H-1975, H1975] is a cell line exhibiting epithelial morphology that was isolated in 1988 from the lungs of a nonsmoking female with non-small cell lung cancer. Use these cells in immuno-oncology and lung cancer research. Homo sapiens, human.
What are pc9 cells?
PC-9 is lung adenocarcinoma cell line with a deletion in exon 19 of the EGFR gene that exhibits high sensitivity to TKIs. The PC-9G cell line (PC-9 cells resistant to gefitinib) was established by long-term exposure to gefitinib, and was shown to harbor the EGFR T790M mutation [10].
How long can you take gefitinib?
The chemotherapy used is a relatively standard regimen of infusions every 3 weeks for four cycles — or 12 weeks of therapy — whereas gefitinib is a daily pill they take for 2 years.
Why was gefitinib withdrawn?
On August 26, 2010, FDA requested that AstraZeneca voluntarily withdraw IRESSA (gefitinib) Tablets from the market, because the postmarketing studies required as a condition of approval under subpart H failed to verify and confirm clinical benefit.
What is the doubling time of HEK cells?
The HEK 293 cell line easily adapted to EX-CELL 293 without forming cellular aggregates and achieved average cell densities of 2.5 x 106 cells/mL in shaker flasks, with an approximate doubling time of 33 hours.
How long does it take for HEK293T cells to adhere?
On resuscitation from frozen, 293 cells will take longer to attach than other cell lines and patience is required as attachment may take several days. 293 cells will detach if their temperature drops below 30°C.