What is Zosyn used to treat?
Zosyn (piperacillin / tazobactam) is a combination antibiotic medication used to treat a wide variety of bacterial infections. It’s only available in injection form, so it’s usually given in the hospital.
Is Zosyn and vancomycin the same?
Zosyn and vancomycin are different types of antibiotics. Zosyn is a combination a penicillin antibiotic and a beta-lactamase inhibitor and vancomycin is a glycopeptide. A brand name of vancomycin is Vancocin. Side effects of Zosyn and vancomycin that are similar include itching.
What is piperacillin tazobactam Zosyn used for?
Piperacillin and tazobactam combination injection is used to treat bacterial infections in many different parts of the body (eg, stomach or bowel, lungs, skin, female reproductive organs).
How is Zosyn administered?
ZOSYN should be administered by intravenous infusion over 30 minutes. The usual total daily dose of ZOSYN for adults is 3.375 g every six hours totaling 13.5 g (12.0 g piperacillin/1.5 g tazobactam). The usual duration of ZOSYN treatment is from 7 to 10 days.
Why is zosyn given over 4 hours?
Summary: EI β-lactam therapy is now considered a key aspect of antimicrobial stewardship, and published evidence indicates that i.v. infusion of piperacillin-tazobactam over extended periods (e.g., four hours) instead of the traditionally recommended 30 minutes may offer several advantages, including reduced mortality …
What are the side effects of ZOSYN?
Nausea, constipation, diarrhea, headache, or trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Can Zosyn cause confusion?
Tell your doctor if you have serious side effects of Zosyn including muscle cramps or spasms, swelling of the arms/legs/hands/feet, easy bruising or bleeding, chest pain, confusion, new signs of infection (such as fever, persistent sore throat), severe abdominal or stomach pain, slow/fast/irregular heartbeat.
What is the generic name for Zosyn?
Zosyn. Generic Name: piperacillin and tazobactam (PI per a SIL in and TAZ oh BAK tam) Brand Name: Zosyn. Medically reviewed by Sophia Entringer, PharmD. Last updated on Sep 1, 2020. Uses. Warnings. Dosage. What to avoid.
What should I know about Zosyn before using it?
While using Zosyn, you may need frequent blood tests. This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Zosyn. Each single-use vial (bottle) of Zosyn is for one use only.
What is Zosyn powder made of?
Zosyn (piperacillin and tazobactam) for Injection, is a white to off-white sterile, cryodesiccated powder consisting of piperacillin and tazobactam as their sodium salts packaged in glass vials. The formulation also contains edetate disodium dihydrate (EDTA) and sodium citrate.
How much sodium is in a Zosyn injection?
Zosyn (piperacillin and tazobactam for injection) contains a total of 2.79 mEq (64 mg) of sodium (Na+) per gram of piperacillin in the combination product. CLINICAL PHARMACOLOGY Peak plasma concentrations of piperacillin and tazobactam are attained immediately after completion of an intravenous infusion of Zosyn.